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The Chicago Climate Exchange (CCX) was North America's first and only voluntary, legally binding greenhouse gas emission reduction and trading system. Founded in 2003 by economist Richard Sandor, CCX allowed member companies to make binding commitments to reduce carbon emissions and trade Carbon Financial Instruments (CFIs). Acquired by ICE (Intercontinental Exchange) in 2010, CCX ceased operations the same year after voluntary carbon credit prices collapsed following the failure of US cap-and-trade legislation.

The New York Mercantile Exchange (NYMEX) is the world's largest physical commodity futures exchange, tracing its origins to 1872 as the Butter and Cheese Exchange of New York. Now a division of CME Group, NYMEX provides global benchmark pricing for energy and metals markets including WTI crude oil, natural gas, heating oil, gasoline, gold, silver, copper, platinum, and palladium. NYMEX contracts are widely referenced for international energy and metals price discovery.

Amercanex is a US-based cannabis commodity exchange headquartered in Denver, Colorado, designed to facilitate transparent wholesale trading of legal cannabis products between licensed growers, processors, and dispensaries. As one of the world's first regulated cannabis commodity exchanges, Amercanex aims to standardise pricing and improve supply-chain efficiency across state-legal cannabis markets.

HedgeStreet Exchange was a CFTC-regulated US derivatives exchange founded in 2004, offering small-denomination binary contracts (starting at $10) on economic events including crude oil prices, gold, natural gas, and macroeconomic indicators. Designed to democratise derivatives access for retail traders, HedgeStreet was one of the first exchanges to offer CFTC-regulated retail binary options on commodity prices. In 2008, the exchange was acquired and eventually rebranded as Cantor Exchange (part of Cantor Fitzgerald), which subsequently ceased operations.